Agrisera's H4K16ac antibody - Histone H4 (ac Lys16) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Precipitation, ChIP, Dot Blot, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot. The H4K16ac antibody - Histone H4 (ac Lys16) was generated using H4 clustered histone 9, H4 histone 16, H4-16, and H4C9 as the antigen and it reacts with Homo Sapiens, and Human.
Description
Common histone modifications include methylation of lysine and arginine, acetylation of lysine, phosphorylation of threonine and serine, and sumoylation, biotinylation, and ubiquitylation of lysine. In particular, acetylation of H4 at Lys16 (H4K16ac) plays a role in transcriptional activation and DNA repair. The protein MOF (MYST1) is the primary enzyme to acetylate K16, along with Gcn5, Esal, ATF2, and Sas2